
Are you at risk of developing heart disease?
According to statistics from the World Heart Federation,
cardiovascular disease - which includes heart diseases and stroke -
is the world's leading cause of death. In Southeast Asia, it
accounts for about 3.5 million deaths every year.
The good news is that heart disease is now mostly preventable and
treatable, thanks to rapid advancements in medical science and
progress with new diagnostic and treatment methods. Still, it is
important to recognise the risk factors and estimate your
susceptibility to coronary heart disease. By understanding and
managing these factors, a patient can substantially lower his or
her risk for heart disease.
What makes you at risk for coronary artery
disease?
There are many risk factors for heart disease.
They are broadly classified into those that are modifiable (can be
changed) and those that are non-modifiable (cannot be changed).

What are the
non-modifiable risk factors?
These are risk factors that you have no control over. They
are:
Age
The older you are, the more
susceptible you are to heart disease. For women, the effects of
menopause - particularly the loss of natural oestrogen - appear to
increase their risks of coronary heart disease and stroke.
Gender
Men are 3 to 5 times more likely to
have coronary heart disease than women. However, the risk for women
increases after menopause. By about 5 to 10 years following
menopause, the risk for coronary heart disease for women increases
to almost the same level as men.
Ethnicity
Risk for coronary heart disease
varies with different ethnic groups. A study done in Singapore
shows that the likelihood for coronary heart disease is highest
amongst South Asians, i.e. Indians,
Pakistanis, Bangladeshis, etc. South Asians are 3 times, and Malays
are 2 times more likely than Chinese to suffer from coronary heart
disease.
Family History
Certain risk factors tend
to run in some families. If there is a history of heart disease in
your immediate family (parents, siblings, children), you should try
very hard to control your modifiable risk factors.

What are the modifiable risk factors?
1) High blood cholesterol
Low-density lipoproteins (LDL) or "bad" cholesterol increases
the build-up of fats in the arteries. This causes hardening of the
arteries so that they become narrowed. The result is that the blood
flow to the heart becomes blocked or reduced.
High-density lipoproteins (HDL) or "good" cholesterol carries
cholesterol from the arteries back to the liver, thus preventing
the build-up of fats and formation of plaque in the arteries.
High blood cholesterol does not cause symptoms. It is therefore
important to check your cholesterol levels regularly. This means
once a year for a normal person wishing to monitor his cholesterol
and more frequently as advised by physicians for those who have
elevated levels or risk factors.
If your cholesterol level is high, it can be lowered to reduce
your susceptibility to coronary heart disease.
The desirable level of cholesterol depends on your pre-existing
risk for coronary heart disease. The goal is to keep your total
cholesterol level as low as possible.

2) High Blood Pressure / Hypertension
Hypertension is one of the major risk factors for coronary heart
disease and cerebrovascular disease such as stroke. You should
check your blood pressure at least once a year.
Like high blood cholesterol, hypertension usually occurs without
any symptoms. If left untreated, it can result in damage to the
heart and blood vessels, eventually leading to stroke, heart attack
or renal failure. Occasionally, when one's blood pressure is
extremely high, the person may experience headaches, dizziness or
alterations in vision.
Normal blood pressure may vary from 90/60mmHg to 120/80mmHg in a
young healthy person. Hypertension is present when a person's blood
pressure is persistently above 140/90mmHg.
If you have diabetes or kidney disease, you must try to keep
your blood pressure at around 120/80mmHg. This is because even a
marginally higher blood pressure will increase your risk of
developing complications.
Marginally elevated blood pressure may normalize when you lose
weight, exercise more and reduce salt intake. If these measures are
not successful, then medication may be needed. However, once
medications have been started, it is essential to continue with the
treatment, which should be complemented with a healthy lifestyle.
Treatment of hypertension for most people is lifelong.

3) Diabetes mellitus and abnormal blood glucose (sugar)
levels
Diabetes mellitus is a chronic illness. People with diabetes are
2 to 4 times more likely to develop coronary artery disease and
stroke. It is often associated with other cardiovascular risk
factors, such as high blood pressure, increased total cholesterol
and triglyceride levels, decreased HDL-cholesterol levels and
obesity.
The basic treatment strategy is to maintain good control over
the amount of glucose in your blood. Maintaining a healthy weight,
a balanced diet and a regular exercise routine can prevent
the onset of diabetes mellitus.

4) Menopause
Before the onset of menopause, many women appear to be partially
protected from coronary heart disease, heart attack and stroke by
natural oestrogen.
A woman's oestrogen level is highest during her childbearing
years and declines during menopause. However, women lose their
natural oestrogen as they age and this may contribute to a higher
risk of heart disease and stroke after menopause.
After menopause, women have a more adverse biochemical profile,
which includes increased triglyceride, very low-density lipoprotein
(VLDL) cholesterol levels or increased LDL or "bad" cholesterol
levels. These changes increase women's risk of developing coronary
heart disease.
If menopause is caused by surgery to remove the uterus and
ovaries, the risk rises sharply. If menopause occurs naturally, the
risk rises gradually. However, routine hormone replacement for
women who have undergone natural menopause does not prevent heart
disease.

5) Obesity and being overweight
People who have excess body fat, especially located around the
waist, are more prone to developing heart disease and stroke even
if they have no other risk factors.
Excess weight increases the strain on the heart and raises blood
pressure, blood cholesterol and triglyceride levels, while lowering
HDL ("good" cholesterol) levels. This may also be associated with
the development of diabetes mellitus.
Family history and environment both play a part in determining
obesity. Body fat increases when you consume more food calories
than you require over a long period of time. Physical inactivity
and a high fat diet also contribute to obesity.
Similarly, weight control (fat loss) is possible by decreasing
food intake while increasing physical activity. If you use more
calories because of increased physical activity, a gradual decrease
in body weight will take place. Weight loss leads to a decrease in
blood pressure, blood glucose and blood cholesterol levels.

6) Physical inactivity
An inactive lifestyle is a risk factor for coronary heart
disease.
Regular physical activity helps prevent heart and blood vessel
disease. Moderate-intensity activities will help if they are done
regularly and over a period of time.
Regular exercise may also lead to improvement in other
cardiovascular risk factors, such as weight loss, lower blood
pressure, decreased stress and improved cholesterol level.
Exercise programmes should start at a slow pace initially to
avoid injury to your muscle and ligaments.
While the risks of exercise are minimal, people with known
coronary artery disease or those above 40 years of age who have
been inactive should seek medical advice before starting a regular
exercise programme.

7) Smoking
Smoking leads to heart attack, stroke, high blood pressure,
blood vessel disease, cancer and lung disease. Smokers have 2 to 3
times the risk of non-smokers of sudden cardiac death. In fact,
smokers account for about 40% of deaths caused by heart disease in
patients who are younger than 65 years.
When a person smokes, the nicotine in the smoke speed up his
heart rate, raise the blood pressure and disturb the flow of blood
and air in the lungs. The carbon monoxide in the smoke lowers the
amount of oxygen carried in the blood to the rest of the person's
body, including the heart and the brain. The tar and cancer-causing
substances are deposited in his airways and lungs.
Smoking also causes a decrease in HDL-cholesterol.

8) Stress
Your blood pressure goes up momentarily when you get angry,
excited, frightened or when you are under stress. If you are
constantly stressed over a prolonged period, you may be at a higher
risk of developing high blood pressure.
Stress affects everyone and may cause palpitation, headaches,
insomnia and digestive symptoms. Prolonged stress may contribute to
a heart attack.
Emotional stress and tension also cause the body to produce
adrenaline, which makes the heart pump faster and harder, and may
also cause the blood vessels to narrow down.

Conclusion
While we cannot do much about the non-modifiable risk factors,
we can still work on the modifiable risk factors to reduce our
risks for coronary heart disease.
Knowing and actively managing our risk factors is the best way
to prevent or delay the onset of heart disease and lessening its
impact on our lives.
This article was contributed by National Heart Centre
Singapore (NHCS) and is part of a series on heart
health.