No, because 7th consciousness, self-consciousness works even
when 6 sense consciousness is temporarily suspended - evident when
we have dreams. Even without dreams the 7th consciousness is there.
Self-consciousness is pre-conscious ('independant' of sense
consciousness) and needs to be dissolved in waking hours through
mindfulness. Only at an advanced stage will we be able to
experience non-dual in sleeping hours.
So the only main difference is lack of 5 sense consciousness in
sleep, and at certain stages of deep sleep there is lesser
thoughts. But the fundamental ignorance is not removed.