Yes! The caterpillar in this instance, is being magnified (its
about as long as my thumbnail) so even the slightest movement is
also magnified, and will affect the photo. And because I'm using a
very small aperture to ensure that the entire caterpillar is sharp,
as well as natural light instead of flash, a relatively long
exposure time of about half a second is needed. 
P.S. I waited for 15 minutes for the breeze to stop before taking
that photo. 
