There really isn't much thats going to happen. Your computer
won't spoil, your documents still there, you system remains.
However, tweaking of a program or in ur chase, your network, will
lead to them not able to work properly if not done right.
Since you asked what tweaking is, i assumed you did not know how to
do it or understand how it work, whatever thing it is you want to
tweak. So i suggest you better get enough info about it first,
fully understand it, before doing things to your network.