Go with your interest, like I want a career in social science,
so I will go with Art stream 
contemplating between H2 bio or phy.I scored C5 for bio for the
O levels but B3 for phy.
I wanna do medicine but i can only have two
sciences(Chem-compulsory + either bio/phy)
I want to do Bio-based course in uni but i fear that it will be
tougher to do well in bio than phy. I also know that if i want to
do medicine,i must take up bio as they will consider Bio students
instead of the Phy students more