Berries belong to cancer-fighting superfoods: study
by Louise Daly
Mon Mar 26, 9:01 AM ET
CHICAGO (AFP) - An antioxidant found in blueberries and grapes may
offer protection against colon cancer, according to a new study
that suggests the humble berry should be added to the list of
cancer-fighting superfoods.
In a small study on rats, the compound appeared to afford the
animals a measure of protection against this type of
malignancy.
All 18 rats were given a compound to induce colon cancer in a
manner similar to human colon cancer development.
Nine of the rodents were then placed on a balanced diet, while the
remainder was given the same diet with a supplement of the berry
antioxidant pterostilbene.
At the end of eight weeks, the rats on pterostilbene had 57 percent
fewer pre-cancerous lesions in their colon in comparison to the
control group.
The compound also reduced colonic cell proliferation and inhibited
certain genes involved in inflammation, both of which are
considered colon cancer risk factors, the researchers reported in a
paper published Sunday at the annual meeting of the American
Chemical Society in Chicago.
"This study underscores the need to include more berries in the
diet, especially blueberries," said Bandaru Reddy, a professor in
the department of Chemical Biology at Rutgers University in New
Jersey.
Further studies are needed to establish exactly what the compound
does, but researchers suspect that its cholesterol-lowering action
may be key given the link between colon cancer and the high level
of saturated fats and calories in Western diets.
Separately, researchers at Ohio State University said they had
begun clinical trials on humans to see if blueberries could prevent
the development of esophageal and colon cancer.
In experiments on rats whose diet was five to 10 percent berries,
the rats had a 60 percent reduction of tumours of the esophagus and
up to an 80 percent reduction in colon tumours.
A third study suggested that chemicals found in grape seed extract
may protect against skin cancer by inhibiting the suppression of
the immune system caused by ultraviolet light exposure, researchers
at the University of Alabama said.
The finding was based on test-tube experiments with mice
cells.
On a related note, Californian researchers reported that organic
produce does offer greater health benefits.
In a head-to-head comparison of organically grown kiwis, versus
traditionally grown kiwis, the organic fruit had significantly
increased levels of polyphenols, a higher overall antioxidant level
and higher levels of Vitamin C.
Both sets of kiwis were grown next to each other on the same farm
at the same time in the same environmental conditions, the
University of California, Davis researchers said.
