KUALA
LUMPUR, Malaysia /PRNewswire/ -- Scientists from the
Department of Medicine at the University of Malaysia have
recently presented the very latest data from a study on colorectal
cancer screening using the M2-PK stool test in the renowned
publication PLOS ONE. These latest results for the M2-PK test from
the cancer specialist Professor Khean-Lee
Goh - one of the most renowned experts
in Asia on
this subject - and his colleagues confirm once again the
exceptionally high capability and accuracy of the M2-PK test for
colorectal cancer screening.
Professor Goh investigated the enyzme biomarker M2-PK in a patient
group with 100 colorectal cancer cases and a population-based
control group of 200 healthy people. The M2-PK test detected 93% of
colorectal cancers. Furthermore, it recognized 97.5% of the control
group as truly healthy. The positive predictive value for
colorectal cancer was 94.9% and the predictive value to exclude
colorectal cancer (negative predictive value) was 96.5%. The
overall accuracy of the M2-PK test was 96%.
The
investigators also made two additional important findings. Firstly,
the M2-PK test has a very high detection rate (sensitivity) for
right-sided (85.7%) as well as for left-sided colorectal cancers
(94.2%). This result is especially important because right-sided
colorectal cancers are more often missed than left-sided with
conventional screening methods.
Secondly, M2-PK had almost the same very high rate of detection
(sensitivity) across all four tumour stages (stage 1 = 94.1%; stage
2 = 88.9%; stage 3 = 96.4%; stage 4 = 90.3%).
The
M2-PK rapid stool test is available for the doctors' practice as
ScheBo®.M2-PK QuickTM (ScheBo.Biotech AG).
Source: K.-L. Goh, et
al.: http://dx.doi.org/10.1371/journal.pone.0131616
ScheBo.Biotech AG / Tel: +49-(0)641-4996-0 / Fax:
+49-(0)641-4996-78 http://www.schebo.com
Source: ScheBo Biotech AG