WASHINGTON — Falling in love
can act as a potent painkiller, and now scientists have figured out
why: It stimulates the brain's reward pathway, much like the rush
of an addictive drug.
The next question is whether better understanding of the
love-pain relationship might somehow help scientists tackle chronic
pain. Falling head over heels isn't exactly something a doctor can
prescribe.
But "maybe prescribing a little passion in one's relationship
can go a long way toward helping with one's chronic pain — assuming
it's passion with the one you're with," said study co-author Dr.
Sean Mackey, chief of pain management at Stanford University.
The neurology of love
The story begins
with psychology professor Arthur Aron of the State University of
New York at Stony Brook, who studies the neurology of love. His
work has linked that euphoric phase of a fresh romance to brain
regions rich in the chemical dopamine. Dopamine is key to what is
called the brain's reward pathway, the feel-good mechanisms that
encourage certain behaviors. Eating sweets, for example, boosts
this system — and addictive drugs like cocaine hijack it.
"When people are in love, in many ways it's not dissimilar to
what they get when they take amphetamines or stimulants: They're
very excited, have loss of appetite, sleep loss, they're active,
full of energy," noted Dr. Nora Volkow, director of the National
Institute on Drug Abuse and a dopamine expert.
Then pain specialists noticed that if someone in an intense
romance gazes at a picture of his or her amour while being poked or
prodded, they feel less pain.
Is that because their love is distracting them from the pain?
After all, specialists often advise sufferers to listen to music or
try other steps to take their mind off the pain. Or did love work
some other way? Mackey and Stanford colleague Dr. Jarred Younger
teamed with Aron to find out.
They put up campus signs seeking love-struck Stanford undergrads
and within hours couples were flocking in, "the easiest study we
have ever recruited for in my entire career," said Mackey.
Fifteen people underwent a battery of tests. They looked at
either a picture of their new love or a picture of an attractive
acquaintance, or were given distracting tasks such as to list
sports that do not involve balls. Researchers touched them with a
hot wand to induce moderate pain, and scanned their brains.
Looking at their loved one and distraction produced equal pain
relief — but the distraction worked through cognitive pathways
while the romance triggered a surge in that reward pathway, the
team reported Wednesday in the journal PLoS One.
That means the brain can generate pain-controlling responses
without medications that perhaps, "if we understood them better, we
could trigger them," said NIDA's Volkow.
Caution: New love's flush can fade to commitment, which does not
trigger the same brain response. But Aron said he recently found
that doing something new and exciting with a longtime partner stirs
up that old passion, "a good idea whether you're in pain or
not."