PSP graphics are better and it might be worth your buying only
if you are going to resort to playing with isos. If not, it is
going to be a hell of a pocket burner.
For the DS, the graphics are not as good, but the games are more
innovative due to the use of a stylus. Games are catered more to
the younger generation (the less hardcore people). The DS doesn't
use isos to play *ahem* type of games, it uses the R4 to play such
games (sold separately).
It depends more on your gaming orientation. Are you more hardcore
or are you just a casual gamer?