Options --> Personal --> My Status --> Untick 'Show me
as "Busy" and block my alerts when I'm running a full-screen
program, such as a slide presentation'
Due to the destructive nature of the almighty Nudge, you'll
probably get jerked right out of your game when someone does it to
you.
If anyone else has a better solution to his problem, I'm interested
to hear about it too. 
