The .50 Desert Eagle pistol for example, not only has a nasty
recoil, it is also too big for most people's hands to grip.
Indeed, the grip is rather large and uncomfortable to hold, but
recoil is surprisingly tolerable due to the sheer
weight of the pistol and the gas-operated recoil mechanism.
A friend of mine has a DE Mk.XIX chambered in 50AE, and shooting
his 300 gr. JHPs through it is actually fun, once you get used to
the massive concussion and muzzle flash. At the local indoor pistol
range, other patrons usually back away from the firing line when
they see you're about to let loose with the DE! 
* Safety is better for when dropped, there is virtually no
chance of the weapon going off unless it was already cocked.
Only if the revolver is equipped with an FP safety. See my
previous post. Also note that if a cocked hammer is accidentally
released when a revolver is dropped, the FP safety will prevent the
hammer from striking the FP.
MG