yes, the above holds true if the time the wheel stays on the
ground is constant.
a larger wheel will have larger inertial mass (we all know that
already i suppose 
) this not only adds rolling resistance, but also, being
unsprung mass, resistance to ur suspension system.
under any given road condition, the suspension will need to keep
the wheels in contact with the ground using the rebound rate of the
shocks as it goes through undulating road conditions (face it, we
dun have sepang tarmac quality). now, the rebound on stock
suspension systems cannot be adjusted. imagine, it would be much
easier for a suspension system to control the oscillation of a
lighter object then that of a heavier one. the danger here is when
one wheel loses contact with the tarmac, a larger rim will take a
longer time to recover its equilibrium compared to a lighter
(smaller rim).
now, the larger contact patch won't make a diff if this
happens.
i dun recommend upsizing ur rims unless u are seriously opting for
lighter (and more expensive) forged rims or have upgraded ur
suspension to some aftermarket ones with adjustable rebound.
