It wll depends on how they are fighting; with, or without
weapons?
If with weapons, unless you know how to disarm and armed person or
two, you best stand aside and let the Police do it. If unarmed,
I'll see how the fight goes, and intervene if either is in danger
of fatal injury.
If drunks are involved, it would be good to break up the fight
before someone gets killed. Then again, it depends on how many are
fighting, and whether weapons are used. No point getting killed
yourself.
But oftentimes, if it is NON OF YOUR BUSINESS, don't get yourself
involved - you might get clobbered as well.
The Police is there for you to call.