yah, just make sure ur hard disk is set to on, but ur monitor
can switch off after 30min or go into screen saver mode.
i leave my laptop and desktop on like continuous for 2 days cuz to
run simulations and jobs and its ok. but monitor i always set to
off after 30min.
surprisingly from my knowledge, the GPU heats up so much faster
than the CPU. Anyway if overheat, the motherboard have safety
features which will automatically switch off the PC when above a
designated temperature. 