Best anti-virus, McAfee, Symantec.
Best anti-spyware, Spybot S-D, Lavasoft Ad-Aware, Hijack-This and
Microsoft Antispyware. For Hijack-This, you need to know a lot
about computers to use it. That's because if you delete the wrong
thing, your system will be gone case. For Microsoft Antispyware,
while it is good, it is pretty heavy on your system resources. And
if you install unknown program, it will keep popping up and ask you
whether you want to allow. Quite an irritating feature.
Recommend you another program: firewall. No firewall = leaving door
open.