Fear conditioning is a form of learning in which fear is
associated with a particular neutral context (e.g., a room) or
neutral stimulus (e.g., a tone). This can be done by pairing the
neutral stimulus with a shock. Eventually, the neutral stimulus
alone brings the animal to the state of fear.
After fear conditioning, fear can be measured in several different
ways. Humans can verbally express or rank their level of fear, but
this is not a reliable measure and cannot be used with animal
subjects. Freezing, a period of watchful immobility, is one of the
most common measures of fear in animals. Fear potentiated startle
is another measure of fear and refers to the augmetation of the
startle reflex by fearful stimulus. Changes in heart rate and
breathing can also be used to measure the fear of an animal or
person subjected to fear conditioning. In most studies, all of
these measures would be taken before and after fear
condtioning.
Fear conditioning is thought to depend upon the amygdala.
Deactivating the amygdala with drugs that block neurotransmitters
prevents both the learning and expression of fear. Other forms of
classical conditioning depend on the cerebellum and the
hippocampus.