Most Epic Punchline Ever. Marvel has nothing on DC here.
In the Invasion
(Arrowverse) crossover featuring The Flash, Arrow, Legends of
Tomorrow and Supergirl, Barry (Flash) was feeling terribly
depressed and blames himself for how, because he went back into the
past to change the timeline for selfish personal reasons, now
everyone's lives have been changed for the worse, and everyone
other than Oliver (Arrow) blames him for this.
So while all the other superheroes go off to fight the alien
invasion, Oliver stays behind to comfort, console and counsel
Barry.

Oliver gives a tear-jerking, heart-rending, emotionally touching
and totally inspirational speech, saying that this is not all
Barry's fault and that he shouldn't blame himself. Barry slowly
opens his heart up, and tearfully hugs Oliver.
5 minutes later, after the aliens somehow managed to
mind-control all the other superheroes, and turn them against Barry
and Oliver. Overpowered by overwhelming force (it's 6 or 7
superheroes versus just Barry & Oliver) and now cornered into
near-death, Oliver screams at Barry, "THIS IS ALL *YOUR* FAULT!!!",
and stunned Barry can only give a silent WTF look.
